Manufacturer with High Purity and Stable Quality
Chemical Name: Azelastine Hydrochloride
CAS: 79307-93-0
Azelastine Hydrochloride is an Histamine H1 Receptor (H1-receptor) antagonist, with antiallergic effects related to histamine antagonism, and further antiallergic and antiinflammatory effects unrelated to H1-receptor binding.
Azelastine Hydrochloride Eye Drops
Azelastine Hydrochloride Nasal Spray
| Chemical Name |
Azelastine Hydrochloride |
| Synonyms |
Azelastine HCl; 4-(4-Chlorobenzyl)-2-(1-methylazepan-4-yl)-1-phthalazinone Hydrochloride |
| CAS Number |
79307-93-0 |
| CAT Number |
RF-API36 |
| Stock Status |
In Stock, Production Scale Up to Tons |
| Molecular Formula |
C22H25Cl2N3O |
| Molecular Weight |
418.36 |
| Melting Point |
223.0~228.0℃ |
| Brand |
Ruifu Chemical |
| Item |
Specifications |
| Appearance |
White or Almost White Crystalline Powder |
| Solubility |
Sparingly soluble in water, soluble in ethanol and in methylene chloride |
| Identification |
(A)By IR absorption, To match with working standard
(B) 1% Solution gives reaction of chlorides |
| Appearance of Solution |
Clear and Colorless |
| Acidity or Alkalinity |
≤0.1 ml of 0.01 mol/L hydrochloric acid or 0.01mol/L sodium hydroxide |
| Related Substances |
|
| Impurities: ABCDE |
≤0.10% |
| Any Other Impurity |
≤0.10% |
| Total Impurities |
≤0.20% |
| Disregard limit |
≤0.05% |
| Loss on Drying |
≤0.50% |
| Assay |
99.0%~101.0% |
| Test Standard |
European Pharmacopeia (EP) |
| Usage |
Active Pharmaceutical Ingredient (API) |
Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer's requirement.
Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.
Azelastine Hydrochloride is a H1 histamine receptor antagonist and NF-kB activator. Azelastine hydrochloride has been used in a study to investigate the potential of polymeric microspheres for treatment of allergic conjunctivitis. Azelastine HCl is an Histamine H1 Receptor (H1-receptor) antagonist, with antiallergic effects related to histamine antagonism, and further antiallergic and antiinflammatory effects unrelated to H1-receptor binding. Azelastine hydrochloride is an orally effective antihistamine useful in the treatment of asthma and nasal allergy. It appears to inhibit release of histamine, in addition to antagonizing its action.