Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of Apremilast (CC-10004) (CAS: 608141-41-9) with high quality, a potent PDE4 (phosphodiesterase 4) inhibitor. Apremilast is used for the treatment of active psoriatic arthritis (PsA) and moderate to severe chronic plaque psoriasis (PSOR).
Ruifu Chemical can provide high-quality Apremilast intermediates and impurities.
Ruifu Chemical can provide worldwide delivery, competitive price, excellent service.
Purchase Apremilast intermediates and impurities or other products, please e-mail: alvin@ruifuchem.com
| Chemical Name | Apremilast |
| Synonyms | Otezla; CC-10004; CC10004; Apster; (S)-N-(2-(1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide; (S)-4-Acetylamino-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]isoindoline-1,3-dione; N-{2-[(1S)-1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl}acetamide; N-{2-[(1S)-1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-1,3-dioxoisoindol-4-yl}acetamide; (S)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione |
| Stock Status | In Stock |
| CAS Number | 608141-41-9 |
| Molecular Formula | C22H24N2O7S |
| Molecular Weight | 460.5 g/mol |
| Melting Point | 152.0~156.0℃ |
| Density | 1.381 g/cm3 |
| Solubility | DMSO (>80 mg/ml) |
| Storage Temperature | Store Long-Term at -20℃ |
| Shipping Conditions | Shipped Under Ambient Temperature for Short Term |
| COA & MSDS | Available |
| Origin of Product | Shanghai, China |
| Product Categories |
API (Active Pharmaceutical Ingredient) |
| Caution | For Research Use Only! Not For Use in Humans! |
| Brand | Ruifu Chemical |
| Items | Specifications | Results |
| Appearance | White to Pale Yellow Solid | Off-White Solid |
| Purity / Analysis Method | >99.0% (HPLC) | 99.5% |
| Infrared Spectrum | Conforms to Structure | Conforms |
| NMR Spectrum | Conforms to Structure | Conforms |
| Conclusion | The product has been tested and complies with the given specifications | |
Package: Bottle, Aluminium foil bag, 25kg/cardboard drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed and store long-term at -20℃. Keep away from incompatible substances. Protect from sunshine; avoid fire and heat sources; avoid moisture.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery.
How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.
Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.
Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.
Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.
Factory Audit? Factory audit welcome. Please make an appointment in advance.
MOQ? No MOQ. Small order is acceptable.
Delivery Time? If within stock, three days delivery guaranteed.
Transportation? By Express (FedEx, DHL), by Air, by Sea.
Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.
Custom Synthesis? Can provide custom synthesis services to best fit your research needs.
Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.
Apremilast (CC-10004; Otezla) (CAS: 608141-41-9) is the first and only oral phosphodiesterase IV (PDE- 4) inhibitor and anti-tumor necrosis factor alpha (TNFa) agent launched in the USA by Celgene for the treatment of active psoriatic arthritis (PsA). Apremilast was also approved for the treatment of moderate to severe plaque psoriasis in the USA. Later, this drug was also approved in the European Union (EU) for both indications.
The listed products which involve patents, are only for research and development ,and not used for sales.
Regulated products will be sold in strict accordance with the laws of China and the laws of the buyer's country.
All products are not for human use ,and all risks associated with the sale to the country that constitutes a patent infringement shall be borne by the buyer.