Manufacturer with High Purity and Stable Quality
Chemical Name: Acotiamide Hydrochloride Trihydrate
CAS: 773092-05-0
In the treatment of postprandial fullness, upper abdominal bloating, and early satiation due to functional dyspepsia.
API High Quality, Commercial Production
| Chemical Name |
Acotiamide Hydrochloride Trihydrate |
| Synonyms |
YM-443, Z-338 |
| CAS Number |
773092-05-0 |
| CAT Number |
RF-API34 |
| Stock Status |
In Stock, Production Scale Up to Hundreds of Kilograms |
| Molecular Formula |
C21H31ClN4O5S |
| Molecular Weight |
487.013 |
| Brand |
Ruifu Chemical |
| Item |
Specifications |
| Appearance |
White or Off-White Powder |
| Purity / Analysis Method |
≥98.0% (HPLC) |
| Residual Solvent Ethanol |
≤0.50% |
| Moisture (K.F) |
9.0%～12.0% |
| Individual Impurity |
≤0.50% |
| Total Impurities |
≤1.0% |
| Residue on Ignition |
≤0.20% |
| 1H NMR |
Corresponds to the Structure |
| Test Standard |
Enterprise Standard |
| Usage |
Active Pharmaceutical Ingredient (API) |
Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer's requirement.
Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.
Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of Acotiamide Hydrochloride Trihydrate (CAS: 773092-05-0) with high quality.
Acotiamide, also known as YM-443 and Z-338, is a drug approved in Japan for the treatment of postprandial fullness, upper abdominal bloating, and early satiation due to functional dyspepsia. It acts as an acetylcholinesterase inhibitor. Note: The Approved drug API is a cotiamide HCl trihydrate (1:1:3). Acotiamide Hydrochloride is the hydrochloride salt form of acotiamide, a prokinetic agent with gastrointestinal (GI) motility-enhancing activity. It is a new orally active selective acetylcholinesterase inhibitor. Acotiamide monohydrochloride trihydrate enhances acetylcholine released by enteric neurons through muscarinic receptor antagonism and acetylcholinesterase (AChE) inhibition, thereby enhancing gastric emptying and gastric accommodation.