Commercial Supply Sorafenib Tosylate and Related Intermediates:
Sorafenib Tosylate CAS: 475207-59-1
Sorafenib CAS: 284461-73-0
4-Chloro-N-Methyl-2-Pyridinecarboxamide CAS: 220000-87-3
4-(4-Aminophenoxy)-N-Methylpicolinamide CAS: 284462-37-9
4-Chloro-3-(Trifluoromethyl)phenyl Isocyanate CAS: 327-78-6
| Chemical Name | 4-Chloro-N-Methyl-2-Pyridinecarboxamide |
| Synonyms | 4-Chloro-N-Methylpicolinamide; N-Methyl-4-Chloropyridine-2-Carboxamide; 4-Chloro-N-Methylpyridine-2-Carboxamide |
| CAS Number | 220000-87-3 |
| CAT Number | RF-PI165 |
| Stock Status | In Stock, Production Scale Up to Tons |
| Molecular Formula | C7H7ClN2O |
| Molecular Weight | 170.60 |
| Melting Point | 41.0~438.0℃ |
| Boiling Point | 317.8℃ at 760 mmHg |
| Density | 1.264 g/cm3 |
| Solubility (Soluble in) | Methanol, Ethylacetate |
| Shipping Conditions | Ambient |
| Brand | Ruifu Chemical |
| Item | Specifications |
| Appearance | Off-White to Light Yellow Powder |
| Identification | (1) MS (2) 1H-NMR |
| Purity / Analysis Method | 98.0%~101.0% (on the dried basis) (HPLC) |
| Moisture (K.F) | ≤1.0% |
| Loss on Drying | ≤1.0% |
| Heavy Metals | ≤20ppm |
| Single Impurity | ≤1.0% |
| Total Impurities | ≤2.0% |
| Test Standard | Enterprise Standard |
| Usage | Intermediate of Sorafenib Tosylate (CAS: 475207-59-1) |
Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer's requirement.
Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.
Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of 4-Chloro-N-Methyl-2-Pyridinecarboxamide (CAS: 220000-87-3) with high quality, it's an intermediate typically in the synthesis of Sorafenib Tosylate (CAS: 475207-59-1). Sorafenib Tosylate is a new type of multi-target antitumor drug, was developed by the German Bayer Pharmaceuticals, and displayed expansive antitumor activity in preclinical animal tests. Sorafenib is available in 200-mg tablets for oral administrationand is used in the treatment of RCC and HCC. Sorafenib Tosylate (CAS: 475207-59-1) can simultaneously affect tumor cells and tumor blood vessels.