| Chemical Name |
2,3,4,6-Tetrakis-O-trimethylsilyl-D-gluconolactone |
| Synonyms |
(3R,4S,5R,6R)-3,4,5-tris(triMethylsilyloxy)-6-((triMethylsilyloxy)Methyl)tetrahydro-2H-pyran-2-one |
| CAS Number |
32384-65-9 |
| CAT Number |
RF-PI233 |
| Stock Status |
In Stock, Production Scale Up to Tons |
| Molecular Formula |
C18H42O6Si4 |
| Molecular Weight |
466.87 |
| Density |
0.97 |
| Brand |
Ruifu Chemical |
| Item |
Specifications |
| Appearance |
Pale Yellow Oily Liquid |
| Purity / Analysis Method |
≥97.0% (GC) |
| Moisture (K.F) |
≤0.50% |
| Test Standard |
Enterprise Standard |
| Usage |
Intermediate of Dapagliflozin(CAS: 461432-26-8) and Canagliflozin (CAS: 842133-18-0) |
Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer's requirement.
Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.
2,3,4,6-Tetrakis-O-trimethylsilyl-D-gluconolactone (CAS: 32384-65-9) is usually used as the intermediate and raw material in the chemistry synthesis and pharmaceutical industry. Especially, this chemical has been widely used in the design and synthesis of sodium-glucose transporter inhibitors. For example, this substance can be employed as raw material in the preparation of (1s)-1,5-anhydro-1-c-[4-chloro-3-[(4-ethoxylphenyl)methyl]phenyl]-D-glucitol, which is commonly known as Dapagliflozin(CAS: 461432-26-8) that act as the sodium dependent glucose transporters for treating type 2 diabetes. Moreover, it can also function as the intermediate for synthesizing Empagliflozin, which is a novel and selective sodium glucose co-transporter-2 inhibitor. In addition, Canagliflozin (CAS: 842133-18-0), another sodium glucose co-transporter-2 inhibitor, can be obtained by utilizing this substance as the intermediate.