Manufacturer Supply Canagliflozin and Related Intermediates:
4-Fluorophenylboronic Acid CAS: 1765-93-1
2-(4-Fluorophenyl)thiophene CAS: 58861-48-6
2,3,4,6-Tetrakis-O-trimethylsilyl-D-gluconolactone CAS: 32384-65-9
5-Iodo-2-Methylbenzoic Acid CAS 54811-38-0
2-(5-Bromo-2-methylbenzyl)-5-(4-fluorophenyl)thiophene CAS: 1030825-20-7
2-(4-Fluorophenyl)-5-[(5-iodo-2-methylphenyl)methyl]thiophene CAS: 898566-17-1
Canagliflozin CAS: 842133-18-0
Canagliflozin Hemihydrate CAS: 928672-86-0
| Chemical Name |
2-(5-Bromo-2-methylbenzyl)-5-(4-fluorophenyl)thiophene |
| Synonyms |
Canagliflozin Intermediate 2; Canagliflozin INT4 |
| CAS Number |
1030825-20-7 |
| CAT Number |
RF-PI234 |
| Stock Status |
In Stock, Production Scale Up to Hundreds of Kilograms |
| Molecular Formula |
C18H14BrFS |
| Molecular Weight |
361.27 |
| Melting Point |
103℃ |
| Density |
1.388 |
| Brand |
Ruifu Chemical |
| Item |
Specifications |
| Appearance |
White or Off-White Powder |
| Purity / Analysis Method |
≥98.0% (HPLC) |
| Loss on Drying |
≤1.0% |
| Residue on ignition |
≤0.5% |
| Heavy Metals |
≤20ppm |
| Test Standard |
Enterprise Standard |
| Usage |
Intermediate of Canagliflozin (CAS: 842133-18-0) |
Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer's requirement.
Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.
Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of 2-(5-Bromo-2-methylbenzyl)-5-(4-fluorophenyl)thiophene (CAS: 1030825-20-7) with high quality. It is an intermediate typically in the synthesis of Dapagliflozin (CAS: 461432-26-8). Dapagliflozin is a new antidiabetic drug jointly developed by Bristol-Myers Squibb and AstraZeneca, being approved by the European Medicines Agency (EMA) on November 12, 2012. It is also the first approved SGLT2 inhibitor for the treatment of type II diabetes, being an important option in the treatment of diabetes, and is used to improve glycemic control as an adjunct to dietary and exercise for adults with type II diabetes.