Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of Methyl 2-Ethoxybenzimidazole-7-Carboxylate (Methyl 2-Ethoxy-1H-Benzo[d]imidazole-7-Carboxylate) (CAS: 150058-27-8) with high quality, intermediate of Candesartan Cilexetil (CAS: 145040-37-5). Ruifu Chemical can provide worldwide delivery, competitive price, excellent service. Purchase Candesartan Cilexetil Intermediates, Please contact: alvin@ruifuchem.com
| Chemical Name | Methyl 2-Ethoxybenzimidazole-7-Carboxylate |
| Synonyms | Methyl 2-Ethoxy-1H-Benzo[d]imidazole-7-Carboxylate; Methyl 2-Ethoxy-1H-Benzimidazole-4-Carboxylate; Methyl 2-Ethoxy-3H-Benzo[d]imidazole-4-Carboxylate; 2-Ethoxy-1H-Benzimidazole-4-carboxylic Acid Methyl Ester; Azilsartan Impurity 38; Candesartan Benzimidazole Ethoxy Impurity |
| Stock Status | In Stock, Commercial Production |
| CAS Number | 150058-27-8 |
| Molecular Formula | C11H12N2O3 |
| Molecular Weight | 220.22 g/mol |
| Melting Point | 130.0~135.0℃ |
| Density | 1.269 |
| Solubility | Soluble in Chloroform, Methanol |
| COA & MSDS | Available |
| Place of Origin | Shanghai, China |
| Brand | Ruifu Chemical |
| Items | Specifications | Results |
| Appearance | Off-White to Light Yellow Powder |
Light Yellow Powder |
| Melting Point | 130.0~135.0℃ | 133.0~133.3℃ |
| Water by Karl Fischer | <0.50% | 0.26% |
| Purity / Analysis Method | >99.0% (HPLC) | 99.92% |
| Infrared Spectrum | Consistent with Structure | Complies |
| Conclusion | The product has been tested and complies with the given specifications | |
| Application | Intermediate of Candesartan Cilexetil (CAS: 145040-37-5) | |
Package: Fluorinated Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed and store in a cool, dry and well-ventilated warehouse away from incompatible substances. Protect from light and moisture.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery.
How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.
Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.
Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.
Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.
Factory Audit? Factory audit welcome. Please make an appointment in advance.
MOQ? No MOQ. Small order is acceptable.
Delivery Time? If within stock, three days delivery guaranteed.
Transportation? By Express (FedEx, DHL), by Air, by Sea.
Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.
Custom Synthesis? Can provide custom synthesis services to best fit your research needs.
Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.
Methyl 2-Ethoxybenzimidazole-7-Carboxylate (Methyl 2-Ethoxy-1H-Benzo[d]imidazole-7-Carboxylate) (CAS: 150058-27-8), intermediate of Candesartan Cilexetil (CAS: 145040-37-5).
Candesartan Cilexetil is a prodrug of the potent, long-acting, and selective angiotensin II type 1 receptor AT1 antagonist, Candesartan. It is rapidly hydrolyzed to Candesartan during gastrointestinal absorption. After hydrolysis of Candesartan Cilexetil to Candesartan during gastrointestinal absorption, Candesartan selectively competes with angiotensin II for the binding of the angiotensin II receptor subtype 1 AT1 in vascular smooth muscle, blocking angiotensin II-mediated vasoconstriction and inducing vasodilatation. In addition, antagonism of AT1 in the adrenal gland inhibits angiotensin II-stimulated aldosterone synthesis and secretion by the adrenal cortex; sodium and water excretion increase, followed by a reduction in plasma volume and blood pressure.