Ruifu Chemical is the leading supplier of 1-Methylpiperazine (CAS: 109-01-3) with high quality.
In the field of pharmaceutical, 1-Methylpiperazine is used as an important pharmaceutical intermediate, can be used in the production of Levofloxacin, Ofloxacin, Fleroxacin and other quinolone anti-infective drugs.
Ruifu Chemical has been supplying piperazines derivatives more than 15 years, can provide worldwide delivery, competitive price, small and bulk quantities available.
If you are interested in piperazines, please send detailed information includes CAS number, product name, quantity to us. Please contact: alvin@ruifuchem.com
| Chemical Name | 1-Methylpiperazine |
| Synonyms | N-Methylpiperazine; 1-Methyl Piperazine; 1-Methyl-Piperazine; N-Methyl Piperazine; Methylpiperazine; NMPRZ |
| Impurity | Imatinib EP Impurity G |
| CAS Number | 109-01-3 |
| Stock Status | In Stock, Production Capacity 100 Tons per Month |
| Molecular Formula | C5H12N2 |
| Molecular Weight | 100.17 |
| Melting Point | -5℃ |
| Boiling Point | 135.0~138.0℃(lit.) |
| Flash Point | 42℃ |
| Density (20℃) | 0.901~0.907 |
| Refractive Index n20/D | 1.464~1.467 |
| Sensitive | Hygroscopic. Moisture Sensitive, Air Sensitive |
| Solubility in Water | Completely Miscible With Water |
| Storage Room Temperature | Cool and Dry Place, Flammable Area |
| Shelf Life | 24 Months From Manufacture Date if Stored Properly |
| COA & MSDS | Available |
| Bulk Order Sample | Available |
| Origin of Product | Shanghai, China |
| Product Categories | Piperazines; Pharmaceutical Intermediates |
| Brand | Ruifu Chemical |
| Item | Specifications | Results |
| Appearance | Colorless to Yellowish Transparent Liquid | Conforms |
| 1-Methylpiperazine | >99.5% (GC) | 99.95% |
| Piperazine | <0.10% | 0.02% |
| N,N'-Dimethylpiperazine | <0.10% | 0.01% |
| Water (by Karl Fischer) | <0.30% | 0.04% |
| Refractive Index n20/D | 1.464-1.467 | 1.465 |
| Total Impurities | <0.50% | Conforms |
| Infrared Spectrum | Conforms to Structure | Conforms |
| Test Standard | Enterprise Standard | Conforms |
Package: Bottle, 25kg/drum; 180kg/drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed. Store in a cool, dry and well-ventilated warehouse away from incompatible substances. Keep away from direct sunlight; avoid fire and heat sources; avoid moisture. Keep upright. Avoid violent collision. Light loading and unloading.
Shipping: Deliver to worldwide by air, by sea, by FedEx / DHL Express. Provide fast and reliable delivery.
How to Purchase? Please contact: sales@ruifuchem.com or alvin@ruifuchem.com
15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.
Main Markets? Sell to domestic market, North America, Europe, India, Russia, Korea, Japanese, Australia, etc.
Advantages? Excellent quality, affordable price, professional services and technical support, fast delivery.
Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.
Factory Audit? Factory audit welcome. Please make an appointment in advance.
MOQ? No MOQ. Small order is acceptable.
Delivery Time? If within stock, three days delivery guaranteed.
Transportation? By Express (FedEx, DHL), by Air, by Sea.
Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.
Custom Synthesis? Can provide custom synthesis services to best fit your research needs.
Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.
Risk Codes
R10 - Flammable
R21 - Harmful in contact with skin
R23 - Toxic by inhalation
R34 - Causes burns
R36/37/38 - Irritating to eyes, respiratory system and skin.
R20/21 - Harmful by inhalation and in contact with skin.
Safety Description
S16 - Keep away from sources of ignition.
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S36 - Wear suitable protective clothing.
UN IDs UN 2734 8/PG 2
WGK Germany 2
RTECS TM1225000
TSCA Yes
HS Code 2934999099
Hazard Note Flammable/Toxic/Corrosive/Store under nitrogen
Hazard Class 3
Packing Group III
1-Methylpiperazine (CAS: 109-01-3) is a piperazine derivative that contains a hydroxy group in the para position. It is used as a organic synthetic intermediates, pharmaceutical intermediates.
1-Methylpiperazine acts as an intermediate in the synthesis of active pharmaceutical ingredients like Levofloxacin, Ofloxacin, Fleroxacin, Rifampicin, Sildenafil, Trifluoperazine, Zopiclone and etc..
1-Methylpiperazine has been used in the third and fourth quinolones antibacterial and anti-inflammatory drugs, erection drugs and anti-tuberculosis drugs.
1-Methylpiperazine can also be used in pesticide, dye, rubber, synthetic fiber, plastic and other industries.
It is expected that the sales of 1-Methylpiperazine will continue to grow in the coming period of time with the increasing demand for applications.
After years of development, the production technology of Ruifu Chemical has been continuously improved, and the quality and production capacity have been continuously improved. Ruifu Chemical is the leading enterprise of 1-Methylpiperazine in China.